Research Articles:
2025
Jia, X., Wang, W., 2025. Unlock the dormant regenerative capacity in mammals by flipping genetic switches. Molecular Therapy 33, 9.
Lin, W., Jia, X., Shi, X., He, Q., Zhang, P., Zhang, X., Zhang, L., Wu, M., Ren, T., Liu, Y., Deng, H., Li, Y., Liu, S., Huang, S., Kang, J., Luo, J., Deng, Z., Wang, W., 2025. Reactivation of mammalian regeneration by turning on an evolutionarily disabled genetic switch. Science 388, eadp0176. 10.1126/science.adp0176.
2024
Ortega Granillo, A., D. Zamora, R. R. Schnittker, A. R. Scott, A. Spluga, J. Russell, C. E. Brewster, E. J. Ross, D. A. Acheampong, N. Zhang, K. Ferro, J. A. Morrison, B. Y. Rubinstein, A. G. Perera, W. Wang, and A. Sanchez Alvarado #. 2024. Positional information modulates transient regeneration-activated cell states during vertebrate appendage regeneration, iScience, 27: 110737.
Harel, I., Chen, Y.R., Ziv, I., Singh, P.P., Heinzer, D., Navarro Negredo, P., Goshtchevsky, U., Wang, W., Astre, G., Moses, E., McKay, A., Machado, B.E., Hebestreit, K., Yin, S., Sanchez Alvarado, A., Jarosz, D.F., Brunet, A., 2024. Identification of protein aggregates in the aging vertebrate brain with prion-like and phase-separation properties. Cell reports, 112787.
Ren, C., Wen, Y., Zheng, S., Zhao, Z., Li, E.Y., Zhao, C., Liao, M., Li, L., Zhang, X., Liu, S., Yuan, D., Luo, K., Wang, W., Fei, J., Li, S., 2024. Two transcriptional cascades orchestrate cockroach leg regeneration. Cell reports 43, 113889.
2023
Jia, X., Lin, W. & Wang, W. Regulation of chromatin organization during animal regeneration. Cell Regeneration, 12, 19 (2023). https://doi.org/10.1186/s13619-023-00162-x
2022
Zhang, JQ., Zhou YQ., Yue, W., Zhu ZS., Wu XL., Yu, S., Shen QY., Pan Q., Xu, WJ., Zhang, R., Wu, XJ., Li, XM., Li, YY, Li, YX., Wang, Y., Peng, S., Zhang, SQ., Lei, AM., Ding, XB., Yang, F., Chen, XQ., Li, N.#, Liao, MZ.#, Wang, W. #, Hua, JL#, 2022. Super-enhancers conserved within placental mammals maintain stem cell pluripotency, Proc Natl Acad Sci U S A, 119 (40) e2204716119. (# Corresponding Authors)
Xiong, SL., Wang, W., Kenzior, A., Olsen, L., Krishnan, J., Persons, J., Medley, K., Peuß, R., Wang, YF., Chen, SY., Zhang, N., Thomas, N., Miles, JM., Sánchez Alvarado, A., Rohner, N., 2022, Enhanced lipogenesis through Pparg helps cavefish adapt to food scarcity, Current Biology 32, 1–9
Before 2021
Wang, W., Hu, C.K., Zeng, A., Alegre, D., Hu, D., Gotting, K., Ortega Granillo, A., Wang, Y., Robb, S., Schnittker, R., Zhang, S., Alegre, D., Li, H., Ross, E., Zhang, N., Brunet, A., Sánchez Alvarado, A., 2020. Changes in regeneration-responsive enhancers shape regenerative capacities in vertebrates. Science 369, (10.1126/science.aaz3090).
Research Highlights in Nature: Why some animals have the power of regeneration.
Research Highlights in Nature Reviews Genetics: Enhancing regeneration.
Kushawah G., Hernandez-Huertas L., Abugattas-Nuñez del Prado J., Martinez-Morales J.R., DeVore M.L., Hassan H., Moreno-Sanchez I., Tomas-Gallardo L., Diaz-Moscoso A., Monges D.C.; Guelfo J.R., Theune W.C., Brannan E.O., Wang W., Corbin T.J., Moran A.M., Sánchez Alvarado A., Málaga-Trillo E., Takacs C.M., Bazzini A.; Moreno-Mateos M., 2020. CRISPR-Cas13d induces efficient mRNA knock-down in animal embryos, Dev. Cell 54, 1–13.
Hu, C.K., Wang, W., Brind’Amour, J., Singh, P.P., Reeves, G.A., Lorincz, M.C., Alvarado, A.S., Brunet, A., 2020. Vertebrate diapause preserves organisms long term through Polycomb complex members. Science 367, 870-874.
Cao, C., Lemaire, L.A., Wang, W., Yoon, P.H., Choi, Y.A., Parsons, L.R., Matese, J.C., Wang, W., Levine, M., Chen, K., 2019. Comprehensive single-cell transcriptome lineages of a proto-vertebrate. Nature 571, 349-354.
Zeng, A., Li, H., Guo, L., Gao, X., McKinney, S., Wang, Y., Yu, Z., Park, J., Semerad, C., Ross, E., Cheng, L.C., Davies, E., Lei, K., Wang, W., Perera, A., Hall, K., Peak, A., Box, A., Sanchez Alvarado, A., 2018. Prospectively Isolated Tetraspanin(+) Neoblasts Are Adult Pluripotent Stem Cells Underlying Planaria Regeneration. Cell 173, 1593-1608 e1520.
Wang, W., Tindell, N., Yan, S., Yoder, J.H., 2013. Homeotic functions of the Teashirt transcription factor during adult Drosophila development. Biology open 2, 18-29.
Wang, W., Yoder, J.H., 2012. Hox-mediated regulation of doublesex sculpts sex-specific abdomen morphology in Drosophila. Dev Dyn 241, 1076-1090.
Wang, W., Kidd, B.J., Carroll, S.B., Yoder, J.H., 2011. Sexually dimorphic regulation of the Wingless morphogen controls sex-specific segment number in Drosophila. Proc Natl Acad Sci U S A 108, 11139-11144.
Wang, W., Yoder, J.H., 2011. Drosophila pupal abdomen immunohistochemistry. J. Vis. Exp. (56), e3139, doi:10.3791/3139
Book Chapters and Protocols:
Wei Wang #, Nicolas Rohner #, and Yongfu Wang #. Book Series: Emerging Model Organisms, Neuromethods, volume 194, 2023. Link for the book: https://doi.org/10.1007/978-1-0716-2875-1. (# Corresponding Editors).
In addition to other models, this book covers essential information for establishing African killifish as a genetic model in the laboratory including fish room design, fish husbandry, gene editing, transgenesis, embryo hatching, in-situ hybridization, and other technologies frequently used in molecular and developmental biology.
Yufei Lou, Weifeng Lin , Wei Wang, 2023. Efficient Transgenesis in African Turquoise Killifish Using a Gibson Assembly–Based Tol2 Transposon System. Cold Spring Harb Protoc.
Ortega Granillo, A. , Schnittker, R. , Wang, W #. and Alvarado, A. S #.(2023). Quantifying cell proliferation through immunofluorescence on whole-mount and cryosectioned regenerating caudal fins in African killifish. Bio Protoc. Dec 20;13(24):e4908. (# Corresponding Authors)